This is fairly old news now, but there was an article in Wired magazine last year on MapSeq, which is a web application developed by Jacob, Olivo, Magnus and Dushy for working with genomic variation data from the malaria parasite.
This is what you’d expect, because there is much more malaria transmission within a region than between different parts of the world. But the interactive plots really come into their own when you start to zoom in on a particular region. You can start to ask questions like, how different are the Thai and Cambodian populations from each other? Are there distinct sub-populations within Thailand or Cambodia?
Of course, the holy grail would be to add a temporal dimension to this. If we could see how parasite populations are changing genetically over time, and relate that to geographical location, we might be able to see drug resistance genes migrating from Cambodia to Thailand – evolution in action! But I’m getting ahead of myself, one step at a time…